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Insights into Cu(I) Exchange in HAH1 using Quantum Mechanical and Molecular Simulations

The human antioxidant protein, HAH1, is an important participant in a Cu(I) transport chain, delivering one Cu(I) ion to the Wilson’s (WND) or Menkes Disease protein (MNK). Full geometry optimizations and second derivative calculations were performed on several binding site models using the B3LYP fu...

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Detalhes bibliográficos
Main Authors: Op’t Holt, Bryan T., Merz, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527583/
https://ncbi.nlm.nih.gov/pubmed/17616150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7007195
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