Inhibition of COX 1 and 2 prior to Renal Ischemia/Reperfusion Injury Decreases the Development of Fibrosis

Ischemia and reperfusion injury (IRI) contributes to the development of chronic interstitial fibrosis/tubular atrophy in renal allograft patients. Cyclooxygenase (COX) 1 and 2 actively participate in acute ischemic injury by activating endothelial cells and inducing oxidative stress. Furthermore, bl...

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Détails bibliographiques
Auteurs principaux: Feitoza, Carla Q, Gonçalves, Giselle M, Semedo, Patrícia, Cenedeze, Marcos A, Pinheiro, Hélady S, Beraldo, Felipe Caetano, dos Santos, Oscar Fernando Pavão, de Paula A Teixeira, Vicente, dos Reis, Marlene A, Mazzali, Marilda, Pacheco-Silva, Alvaro, Câmara, Niels O S
Format: Artigo
Langue:Inglês
Publié: ScholarOne 2008
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527343/
https://ncbi.nlm.nih.gov/pubmed/18769637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2008-00064.Feitoza
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