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Biomarkers for ragwort poisoning in horses: identification of protein targets

BACKGROUND: Ingestion of the poisonous weed ragwort (Senecio jacobea) by horses leads to irreversible liver damage. The principal toxins of ragwort are the pyrrolizidine alkaloids that are rapidly metabolised to highly reactive and cytotoxic pyrroles, which can escape into the circulation and bind t...

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Hlavní autoři: Moore, Rowan E, Knottenbelt, Derek, Matthews, Jacqueline B, Beynon, Robert J, Whitfield, Phillip D
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527303/
https://ncbi.nlm.nih.gov/pubmed/18691403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-4-30
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