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Human eosinophil adhesion and degranulation stimulated with eotaxin and RANTES in vitro: Lack of interaction with nitric oxide

BACKGROUND: Airway eosinophilia is considered a central event in the pathogenesis of asthma. The toxic components of eosinophils are thought to be important in inducing bronchial mucosal injury and dysfunction. Previous studies have suggested an interaction between nitric oxide (NO) and chemokines i...

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Bibliographic Details
Main Authors: Lintomen, Letícia, Franchi, Gilberto, Nowill, Alexandre, Condino-Neto, Antonio, de Nucci, Gilberto, Zanesco, Angelina, Antunes, Edson
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527293/
https://ncbi.nlm.nih.gov/pubmed/18700028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-8-13
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