Structural Flexibility of the Pentameric SARS Coronavirus Envelope Protein Ion Channel

Coronaviruses contain a small envelope membrane protein with cation-selective ion channel activity mediated by its transmembrane domain (ETM). In a computational study, we proposed that ion channel activity can be explained by either of two similar ETM homopentameric transmembrane α-helical bundles,...

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Bibliographic Details
Main Authors: Parthasarathy, Krupakar, Ng, Lifang, Lin, Xin, Liu, Ding Xiang, Pervushin, Konstantin, Gong, Xiandi, Torres, Jaume
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Biophysical Letters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527252/
https://ncbi.nlm.nih.gov/pubmed/18658207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.133041
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