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Epithelial sodium channel is a key mediator of growth hormone-induced sodium retention in acromegaly

Acromegalic patients present with volume expansion and arterial hypertension but the renal sites and molecular mechanisms of direct antinatriuretic action of growth hormone (GH) remain unclear. Here, we show that acromegalic GC rats, which are chronically exposed to very high levels of GH, exhibited...

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Detalhes bibliográficos
Main Authors: Kamenicky, Peter, Viengchareun, Say, Blanchard, Anne, Meduri, Geri, Zizzari, Philippe, Imbert-Teboul, Martine, Doucet, Alain, Chanson, Philippe, Lombes, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527214/
https://ncbi.nlm.nih.gov/pubmed/18388193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0143
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