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Significance of the gastrin homology and surrounding sequences in polyomavirus middle T antigen for cell transformation.

Deletion of residues 305 to 327 of polyomavirus middle T antigen, including the (Glu)6-Tyr-315 sequence that is a preferred site of phosphorylation in vitro by pp60c-src, markedly altered viral transformation of rat cells. The efficiency of transformation by the deletion mutant depended on how it wa...

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Bibliographic Details
Published in:J Virol
Main Authors: Clark, K L, Folk, W R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252720/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3001348/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.57.1.237-245.1986
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