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Cocaine Self-Administration Produces a Persistent Increase in Dopamine D2(High) Receptors

Cocaine addicts are reported to have decreased numbers of striatal dopamine D2 receptors. However, in rodents, repeated cocaine administration consistently produces hypersensitivity to the psychomotor activating effects of both indirect dopamine agonists, such as cocaine itself, and importantly, to...

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Detalhes bibliográficos
Main Authors: Briand, Lisa A., Flagel, Shelly B., Seeman, Philip, Robinson, Terry E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527181/
https://ncbi.nlm.nih.gov/pubmed/18284941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2008.01.002
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