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The Basis for Selective E1-E2 Interactions in the ISG15 Conjugation System

E1 and E2 enzymes coordinate the first steps in conjugation of ubiquitin (Ub) and ubiquitin-like proteins (Ubls). ISG15 is an interferon-α/β-induced Ubl, and the E1 and E2 enzymes for ISG15 conjugation are Ube1L and UbcH8, respectively. UbcH7 is the most closely related E2 to UbcH8, yet it does not...

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Detalhes bibliográficos
Main Authors: Durfee, Larissa A., Kelley, Melissa L., Huibregtse, Jon M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527107/
https://ncbi.nlm.nih.gov/pubmed/18583345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804069200
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