Granulysin Produced by Uterine Natural Killer Cells Induces Apoptosis of Extravillous Trophoblasts in Spontaneous Abortion

Immune changes are known to occur in recurrent spontaneous abortion, but it is unclear whether either maternal natural killer (NK) cells or T cells attack fetus-derived trophoblasts. To clarify the immunological causes of spontaneous abortion, we examined the relationship between cytotoxic granule p...

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Detalhes bibliográficos
Main Authors: Nakashima, Akitoshi, Shiozaki, Arihiro, Myojo, Subaru, Ito, Mika, Tatematsu, Mikiko, Sakai, Masatoshi, Takamori, Yasushi, Ogawa, Kazuyuki, Nagata, Kinya, Saito, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527087/
https://ncbi.nlm.nih.gov/pubmed/18688023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071169
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