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Soluble Forms of the Notch Ligands Delta1 and Jagged1 Promote in Vivo Tumorigenicity in NIH3T3 Fibroblasts with Distinct Phenotypes

We previously found that soluble forms of the Notch ligands Jagged1 and Delta1 induced fibroblast growth factor receptor-dependent cell transformation in NIH3T3 fibroblasts. However, the phenotypes of these lines differed, indicating distinct functional differences among these Notch ligands. In the...

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Detalhes bibliográficos
Main Authors: Urs, Sumithra, Roudabush, Alice, O'Neill, Christine F., Pinz, Ilka, Prudovsky, Igor, Kacer, Doreen, Tang, Yuefang, Liaw, Lucy, Small, Deena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527077/
https://ncbi.nlm.nih.gov/pubmed/18688026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080006
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