Soluble Forms of the Notch Ligands Delta1 and Jagged1 Promote in Vivo Tumorigenicity in NIH3T3 Fibroblasts with Distinct Phenotypes

We previously found that soluble forms of the Notch ligands Jagged1 and Delta1 induced fibroblast growth factor receptor-dependent cell transformation in NIH3T3 fibroblasts. However, the phenotypes of these lines differed, indicating distinct functional differences among these Notch ligands. In the...

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Hlavní autoři: Urs, Sumithra, Roudabush, Alice, O'Neill, Christine F., Pinz, Ilka, Prudovsky, Igor, Kacer, Doreen, Tang, Yuefang, Liaw, Lucy, Small, Deena
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2008
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527077/
https://ncbi.nlm.nih.gov/pubmed/18688026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080006
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