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Hedgehog Signaling, Keratin 6 Induction, and Sebaceous Gland Morphogenesis : Implications for Pachyonychia Congenita and Related Conditions

Keratins 6a and b (K6a, K6b) belong to a subset of keratin genes with constitutive expression in epithelial appendages, and inducible expression in additional epithelia, when subjected to environmental challenges or disease. Mutations in K6a or K6b cause a broad spectrum of epithelial lesions that d...

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Autori principali: Gu, Li-Hong, Coulombe, Pierre A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527074/
https://ncbi.nlm.nih.gov/pubmed/18688029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071089
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