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TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens

In several tumors the transketolase activity, controlled inter alia by enzymes of the pentose phosphate pathway which is an alternative, energy generating reaction-cascade to glycolysis, has been correlated with proliferation. The increase of thiamine-dependant transketolase enzyme reactions is indu...

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Autores principales: Schultz, Holger, Kähler, Daniel, Branscheid, Detlev, Vollmer, Ekkehard, Zabel, Peter, Goldmann, Torsten
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526982/
https://ncbi.nlm.nih.gov/pubmed/18700018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-3-35
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