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Isolation and analysis of adenovirus type 5 mutants containing deletions in the gene encoding the DNA-binding protein.

A genetic system is described which allows the isolation and propagation of adenovirus mutants containing lesions in early region 2A (E2A), the gene encoding the multifunctional adenovirus DNA-binding protein (DBP). A cloned E2A gene was first mutagenized in vitro and then was introduced into the vi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Rice, S A, Klessig, D F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3864995/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.56.3.767-778.1985
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