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Two independent mutations are required for temperature-sensitive cell transformation by a Rous sarcoma virus temperature-sensitive mutant.

We molecularly cloned the src coding region of tsNY68, a mutant of Rous sarcoma virus temperature sensitive (ts) for transformation, and constructed a series of ts wild-type recombinant src genes. DNA containing the hybrid genes was transfected into chicken cells together with viral vector DNA and h...

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Autors principals: Nishizawa, M, Mayer, B J, Takeya, T, Yamamoto, T, Toyoshima, K, Hanafusa, H, Kawai, S
Format: Artigo
Idioma:Inglês
Publicat: 1985
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC252644/
https://ncbi.nlm.nih.gov/pubmed/2999430
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