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Orientation and Oligomerization Specificity of the Bcr Coiled-Coil Oligomerization Domain
The Bcr oligomerization domain, from the Bcr-Abl oncoprotein, is an attractive therapeutic target for treating leukemias because it is required for cellular transformation. The domain homodimerizes via an antiparallel coiled coil with an adjacent short, helical swap domain. Inspection of the coiled-...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2526250/ https://ncbi.nlm.nih.gov/pubmed/16331985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051493t |
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