The human paraoxonase-1 phenotype modifies the effect of statins on paraoxonase activity and lipid parameters

AIMS: Human serum paraoxonase-1 (PON1) protects lipoproteins against oxidation by hydrolysing lipid peroxides in oxidized low-density lipoprotein, therefore it may protect against atherosclerosis. One of the two common PON1 gene polymorphisms within the PON1 gene is the Q192R, whose prevalence can b...

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Hlavní autoři: Mirdamadi, Hossein Z, Sztanek, Ferenc, Derdak, Zoltan, Seres, Ildiko, Harangi, Mariann, Paragh, György
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2008
Témata:
Pharmacogenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526235/
https://ncbi.nlm.nih.gov/pubmed/18492126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03213.x
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