Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection

The inflamed liver in chronic hepatitis B virus (HBV) infection (CHB) is characterized by a large influx of non–virus-specific CD8 T cells. Little is known about the functional capacity of these lymphocytes, which could provide insights into mechanisms of failure of viral control and liver damage in...

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Detalhes bibliográficos
Main Authors: Das, Abhishek, Hoare, Matthew, Davies, Nathan, Lopes, A. Ross, Dunn, Claire, Kennedy, Patrick T.F., Alexander, Graeme, Finney, Helene, Lawson, Alistair, Plunkett, Fiona J., Bertoletti, Antonio, Akbar, Arne N., Maini, Mala K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526205/
https://ncbi.nlm.nih.gov/pubmed/18695005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072076
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