Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection

D6 is a decoy and scavenger receptor for inflammatory CC chemokines. D6-deficient mice were rapidly killed by intranasal administration of low doses of Mycobacterium tuberculosis. The death of D6(−/−) mice was associated with a dramatic local and systemic inflammatory response with levels of M. tube...

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Detalhes bibliográficos
Main Authors: Di Liberto, Diana, Locati, Massimo, Caccamo, Nadia, Vecchi, Annunciata, Meraviglia, Serena, Salerno, Alfredo, Sireci, Guido, Nebuloni, Manuela, Caceres, Neus, Cardona, Pere-Joan, Dieli, Francesco, Mantovani, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526202/
https://ncbi.nlm.nih.gov/pubmed/18695004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070608
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