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Metabolic Dynamics in Skeletal Muscle during Acute Reduction in Blood Flow and Oxygen Supply to Mitochondria: In-Silico Studies Using a Multi-Scale, Top-Down Integrated Model

Control mechanisms of cellular metabolism and energetics in skeletal muscle that may become evident in response to physiological stresses such as reduction in blood flow and oxygen supply to mitochondria can be quantitatively understood using a multi-scale computational model. The analysis of dynami...

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Detalhes bibliográficos
Main Authors: Dash, Ranjan K., Li, Yanjun, Kim, Jaeyeon, Beard, Daniel A., Saidel, Gerald M., Cabrera, Marco E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526172/
https://ncbi.nlm.nih.gov/pubmed/18779864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003168
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