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Effects of chronic central leptin infusion on proopiomelanocortin and neurotensin gene expression in the rat hypothalamus
Leptin signaling in the hypothalamus is critical for normal food intake and body weight regulation. While hyperleptinemia in obese people suggests a state of leptin resistance, the mechanism is not clearly understood. In a rat model of central leptin infusion in which animals develop resistance to t...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2526046/ https://ncbi.nlm.nih.gov/pubmed/18562101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.05.083 |
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