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Characterization of a temperature-sensitive mutant of vaccinia virus reveals a novel function that prevents virus-induced breakdown of RNA.

We have attempted to characterize the molecular defect in a temperature-sensitive mutant of vaccinia virus, ts22, which has an abortive late phenotype. At the nonpermissive temperature, ts22 displays normal viral protein synthesis until 8 h postinfection. Between 8 and 10 h after infection all viral...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Pacha, R F, Condit, R C
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1985
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252592/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4057355/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.56.2.395-403.1985
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