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The haemotoxicity of azathioprine in repeat dose studies in the female CD-1 mouse

Azathioprine (AZA) is a cytotoxic immunosuppressive drug used in the prevention of rejection in organ transplants and the treatment of auto-immune diseases. However, AZA is haemotoxic causing significant bone marrow depression. The present studies were to characterize the haemotoxicity of AZA in the...

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Detalhes bibliográficos
Main Authors: Molyneux, Gemma, Gibson, Frances M, Chen, Christabelle M, Marway, Harpal K, McKeag, Sean, Mifsud, Charles V J, Pilling, Andrew M, Whayman, Matthew J, Turton, John A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525763/
https://ncbi.nlm.nih.gov/pubmed/18336531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2008.00575.x
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