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TNF-α and glucocorticoid receptor interaction in L6 muscle cells : A cooperative downregulation of myosin heavy chain
Sepsis is associated with increased expression of TNF-α with subsequent activation of nuclear factor-kappa B (NF-κB). The glucocorticoid receptor (GR) and NF-κB function as mutual antagonists and induction of the latter is believed to play a major role in the acquired glucocorticoid resistance that...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525668/ https://ncbi.nlm.nih.gov/pubmed/17624386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2007.05.007 |
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