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Interferon γ–independent Rejection of Interleukin 12–transduced Carcinoma Cells Requires CD4(+) T Cells and Granulocyte/Macrophage Colony–stimulating Factor
We analyzed the ability of interferon (IFN)-γ knockout mice (GKO) to reject a colon carcinoma transduced with interleukin (IL)-12 genes (C26/IL-12). Although the absence of IFN-γ impaired the early response and reduced the time to tumor onset in GKO mice, the overall tumor take rate was similar to t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525540/ https://ncbi.nlm.nih.gov/pubmed/9653090 |
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