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Restoring full biological activity to the isolated ectodomain of an integral membrane protein
Integral membrane proteins, which include many cellular effector proteins and drug targets, can be difficult to produce, purify and manipulate. Although the isolated ectodomains of many membrane proteins can be expressed as water soluble proteins, biological activity is frequently lost when these pr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525505/ https://ncbi.nlm.nih.gov/pubmed/16533060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052600m |
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