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Binding of Signal Recognition Particle Gives Ribosome/Nascent Chain Complexes a Competitive Advantage in Endoplasmic Reticulum Membrane Interaction

Most secretory and membrane proteins are sorted by signal sequences to the endoplasmic reticulum (ER) membrane early during their synthesis. Targeting of the ribosome-nascent chain complex (RNC) involves the binding of the signal sequence to the signal recognition particle (SRP), followed by an inte...

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Udgivet i:Mol Biol Cell
Principais autores: Neuhof, Andrea, Rolls, Melissa M., Jungnickel, Berit, Kalies, Kai-Uwe, Rapoport, Tom A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 1998
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25224/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9436994/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.1.103
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