Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E(2) results in high interleukin-12 production and cell migration

Dendritic cells (DC) are professional antigen-presenting cells of the immune system that play a key role in regulating T cell-based immunity. In vivo, the capacity of DC to activate T cells depends on their ability to migrate to the T cell areas of lymph nodes as well as on their maturation state. D...

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Main Authors: Boullart, A. C. Inge, Aarntzen, Erik H. J. G., Verdijk, Pauline, Jacobs, Joannes F. M., Schuurhuis, Danita H., Benitez-Ribas, Daniel, Schreibelt, Gerty, van de Rakt, Mandy W. M. M., Scharenborg, Nicole M., de Boer, Annemiek, Kramer, Matthijs, Figdor, Carl G., Punt, Cornelis J. A., Adema, Gosse J., de Vries, I. Jolanda M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522299/
https://ncbi.nlm.nih.gov/pubmed/18322684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0489-2
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