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Extraction of Cholesterol with Methyl-β-Cyclodextrin Perturbs Formation of Clathrin-coated Endocytic Vesicles

The importance of cholesterol for endocytosis has been investigated in HEp-2 and other cell lines by using methyl-β-cyclodextrin (MβCD) to selectively extract cholesterol from the plasma membrane. MβCD treatment strongly inhibited endocytosis of transferrin and EGF, whereas endocytosis of ricin was...

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Detalhes bibliográficos
Main Authors: Rodal, Siv Kjersti, Skretting, Grethe, Garred, Øystein, Vilhardt, Frederik, van Deurs, Bo, Sandvig, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25220/
https://ncbi.nlm.nih.gov/pubmed/10198050
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