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Isoleucine and Valine Metabolism of Escherichia coli XV. Biochemical Properties of Mutants Resistant to Thiaisoleucine

Thiaisoleucine-resistant mutants of Escherichia coli strain K-12 which exhibited reduced isoleucyl soluble ribonucleic acid synthetase activity were isolated. Resistance was apparently achieved by the selection of a synthetase with a 10-fold decrease in apparent affinity for thiaisoleucine. This mut...

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Detalhes bibliográficos
Main Authors: Szentirmai, A., Szentirmai, M., Umbarger, H. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1968
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC252194/
https://ncbi.nlm.nih.gov/pubmed/4297021
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