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Specific Activation of Leukocyte β2 Integrins Lymphocyte Function–associated Antigen-1 and Mac-1 by Chemokines Mediated by Distinct Pathways via the α Subunit Cytoplasmic Domains

We show that CC chemokines induced a sustained increase in monocyte adhesion to intercellular adhesion molecule-1 that was mediated by Mac-1 (αMβ2) but not lymphocyte function–associated antigen-1 (LFA-1; αLβ2). In contrast, staining for an activation epitope revealed a rapid and transient up-regula...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Mol Biol Cell
Ngā kaituhi matua: Weber, Kim S.C., Klickstein, Lloyd B., Weber, Christian
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Cell Biology 1999
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25207/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10198043/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.4.861
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