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Cdc25 Inhibited In Vivo and In Vitro by Checkpoint Kinases Cds1 and Chk1

In the fission yeast Schizosaccharomyces pombe, the protein kinase Cds1 is activated by the S–M replication checkpoint that prevents mitosis when DNA is incompletely replicated. Cds1 is proposed to regulate Wee1 and Mik1, two tyrosine kinases that inhibit the mitotic kinase Cdc2. Here, we present ev...

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Detalhes bibliográficos
Main Authors: Furnari, Beth, Blasina, Alessandra, Boddy, Michael N., McGowan, Clare H., Russell, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25205/
https://ncbi.nlm.nih.gov/pubmed/10198041
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