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Microdialysis sampling with on-line microbore HPLC for the determination of tirapazamine and its reduced metabolites in rats

An on-line microdialysis microbore HPLC method is described for the determination of the bioreductive anti-tumor agent, tirapazamine (3-amino-1,2,4-benzotriazine-1,4-di-N-oxide, SR4233, WIN59075, Tirazone, TPZ) and its two major reduced metabolites, 3-amino-1,2,4-benzotriazine-1-N-oxide (SR4317) and...

詳細記述

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書誌詳細
主要な著者: McLaughlin, Kieran J., Faibushevich, Alexander A., Lunte, Craig E.
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519821/
https://ncbi.nlm.nih.gov/pubmed/10885067
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