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Application of capillary electrophoresis with pH-mediated sample stacking to analysis of coumarin metabolites in microsomal incubations

A sensitive method for the analysis of metabolites of coumarin by capillary electrophoresis (CE), incorporating pH-mediated sample stacking, was developed. The analytes were detected in phosphate buffer (pH 7.5; 25 mM), the matrix of the microsomal incubations. Detection was by direct UV absorbance....

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Detalhes bibliográficos
Main Authors: Ward, Eimear M., Smyth, Malcolm R., O’Kennedy, Richard, Lunte, Craig E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519807/
https://ncbi.nlm.nih.gov/pubmed/12899967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0731-7085(03)00184-5
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