Cardioselective dominant-negative thyroid hormone receptor (Δ337T) modulates myocardial metabolism and contractile efficiency

Dominant-negative thyroid hormone receptors (TRs) show elevated expression relative to ligand-binding TRs during cardiac hypertrophy. We tested the hypothesis that overexpression of a dominant-negative TR alters cardiac metabolism and contractile efficiency (CE). We used mice expressing the cardiose...

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Detalhes bibliográficos
Main Authors: Hyyti, Outi M., Olson, Aaron K., Ge, Ming, Ning, Xue-Han, Buroker, Norman E., Chung, Youngran, Jue, Thomas, Portman, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519753/
https://ncbi.nlm.nih.gov/pubmed/18523124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90329.2008
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