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Deficiency of glucose-dependent insulinotropic polypeptide receptor prevents ovariectomy-induced obesity in mice

Menopause and premature gonadal steroid deficiency are associated with increases in fat mass and body weight. Ovariectomized (OVX) mice also show reduced locomotor activity. Glucose-dependent-insulinotropic-polypeptide (GIP) is known to play an important role both in fat metabolism and locomotor act...

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Autores principales: Isken, Frank, Pfeiffer, Andreas F. H., Nogueiras, Rubén, Osterhoff, Martin A., Ristow, Michael, Thorens, Bernard, Tschöp, Matthias H., Weickert, Martin O.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519752/
https://ncbi.nlm.nih.gov/pubmed/18505834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00008.2008
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