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Sumo-1 Function Is Dispensable in Normal Mouse Development
To elucidate SUMO-1 functions in vivo, we targeted by homologous recombination the last three exons of the murine Sumo-1 gene. Sumo-1 mRNA abundance was reduced to one-half in heterozygotes and was undetectable in Sumo-1(−/−) mice, and SUMO-1-conjugated RanGAP1 was detectable in wild-type mouse embr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519746/ https://ncbi.nlm.nih.gov/pubmed/18573887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00651-08 |
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