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Phosphorylated Ssk1 Prevents Unphosphorylated Ssk1 from Activating the Ssk2 Mitogen-Activated Protein Kinase Kinase Kinase in the Yeast High-Osmolarity Glycerol Osmoregulatory Pathway

In Saccharomyces cerevisiae, external high osmolarity activates the Hog1 mitogen-activated protein kinase (MAPK), which controls various aspects of osmoadaptation. Ssk1 is a homolog of bacterial two-component response regulators and activates the Ssk2 MAPK kinase kinase upstream of Hog1. It has been...

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Autores principales: Horie, Tetsuro, Tatebayashi, Kazuo, Yamada, Rika, Saito, Haruo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519728/
https://ncbi.nlm.nih.gov/pubmed/18573873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00589-08
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