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Structural Insight into the Human Immunodeficiency Virus Vif SOCS Box and Its Role in Human E3 Ubiquitin Ligase Assembly

Human immunodeficiency virus (HIV) virion infectivity factor (Vif) causes the proteasome-mediated destruction of human antiviral protein APOBEC3G by tethering it to a cellular E3 ubiquitin ligase composed of ElonginB, ElonginC, Cullin5, and Rbx2. It has been proposed that HIV Vif hijacks the E3 liga...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stanley, Bradford J., Ehrlich, Elana S., Short, Leslie, Yu, Yunkai, Xiao, Zuoxiang, Yu, Xiao-Fang, Xiong, Yong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519636/
https://ncbi.nlm.nih.gov/pubmed/18562529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00767-08
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