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Temporary Depletion of CD11c(+) Dendritic Cells Delays Lymphoinvasion after Intraperitonal Scrapie Infection

The involvement of immune cells in prion capture and transport to lymphoid tissues still remains unclear. To investigate the role of dendritic cells (DC), we used DTR(+/+) mice, a transgenic model designed to trigger short-term ablation of DC. Transient depletion of DC around the time of intraperito...

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Bibliografiska uppgifter
Huvudupphovsmän: Cordier-Dirikoc, Sevda, Chabry, Joëlle
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519635/
https://ncbi.nlm.nih.gov/pubmed/18579603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02440-07
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