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Activation of Akt through gp130 Receptor Signaling Is Required for Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphatic Reprogramming of Endothelial Cells

Kaposi's sarcoma (KS) is the most common tumor of AIDS patients worldwide. KS-associated herpesvirus (KSHV) is the infectious cause of this highly vascularized skin tumor. The main cell type found within a KS lesion, the spindle cell, is latently infected with KSHV and has markers of both blood...

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Detalhes bibliográficos
Main Authors: Morris, Valerie A., Punjabi, Almira S., Lagunoff, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519632/
https://ncbi.nlm.nih.gov/pubmed/18579585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00766-08
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