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Nuclear Import of the Varicella-Zoster Virus Latency-Associated Protein ORF63 in Primary Neurons Requires Expression of the Lytic Protein ORF61 and Occurs in a Proteasome-Dependent Manner

Varicella-zoster virus (VZV) open reading frame (ORF) 63 protein (ORF63p) is one of six VZV ORFs shown to be transcribed and translated in latently infected human dorsal root ganglia. ORF63p accumulates exclusively in the cytoplasm of latently infected sensory neurons, whereas it is both nuclear and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Walters, Matthew S., Kyratsous, Christos A., Wan, Shilin, Silverstein, Saul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519623/
https://ncbi.nlm.nih.gov/pubmed/18562514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00685-08
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