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In Vivo Potential Effects of Adenovirus Type 5 E1A and E1B on Lung Carcinogenesis and Lymphoproliferative Inflammation

Triggering uncontrolled cellular proliferation, chronic inflammation, and/or disruption of p53 activity is critical for tumorigenesis initiated by latent viral oncogenes. The adenovirus type 5 (Ad5) early genes E1A and E1B can maintain lifelong latency in the lungs of patients with chronic pulmonary...

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Detalhes bibliográficos
Main Authors: Yang, Yongping, McKerlie, Colin, Lu, Zhan, Wang, Lena, Buchwald, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519581/
https://ncbi.nlm.nih.gov/pubmed/18524829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00536-08
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