Type III Secretion Decreases Bacterial and Host Survival following Phagocytosis of Yersinia pseudotuberculosis by Macrophages

Yersinia pseudotuberculosis uses a plasmid (pYV)-encoded type III secretion system (T3SS) to translocate a set of effectors called Yops into infected host cells. YopJ functions to induce apoptosis, and YopT, YopE, and YopH act to antagonize phagocytosis in macrophages. Because Yops do not completely...

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Detalhes bibliográficos
Main Authors: Zhang, Yue, Murtha, James, Roberts, Margaret A., Siegel, Richard M., Bliska, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519449/
https://ncbi.nlm.nih.gov/pubmed/18591234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00183-08
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