The Interleukin-17 Receptor Plays a Gender-Dependent Role in Host Protection against Porphyromonas gingivalis-Induced Periodontal Bone Loss

Interleukin-17 (IL-17) is a proinflammatory cytokine secreted by the newly described CD4(+) Th17 subset, which is distinct from classic Th1 and Th2 lineages. IL-17 contributes to bone destruction in rheumatoid arthritis but is essential in host defense against pathogens that are susceptible to neutr...

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Bibliographic Details
Main Authors: Yu, Jeffrey J., Ruddy, Matthew J., Conti, Heather R., Boonanantanasarn, Kanitsak, Gaffen, Sarah L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519446/
https://ncbi.nlm.nih.gov/pubmed/18591228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01209-07
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