Alterations of Splenic Architecture in Malaria Are Induced Independently of Toll-Like Receptors 2, 4, and 9 or MyD88 and May Affect Antibody Affinity

Splenic microarchitecture is substantially altered during acute malaria infections, which may affect the development and regulation of immune responses. Here we investigated whether engagement of host Toll-like receptor 2 (TLR2), TLR4, TLR9, and the adaptor protein MyD88 is required for induction of...

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Detalhes bibliográficos
Main Authors: Cadman, Emma T., Abdallah, Asmahan Y., Voisine, Cécile, Sponaas, Anne-Marit, Corran, Patrick, Lamb, Tracey, Brown, Douglas, Ndungu, Francis, Langhorne, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519400/
https://ncbi.nlm.nih.gov/pubmed/18559428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00372-08
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