Use of Vaxfectin Adjuvant with DNA Vaccine Encoding the Measles Virus Hemagglutinin and Fusion Proteins Protects Juvenile and Infant Rhesus Macaques against Measles Virus

A measles virus vaccine for infants under 6 months of age would help control measles. DNA vaccines hold promise, but none has provided full protection from challenge. Codon-optimized plasmid DNAs encoding the measles virus hemagglutinin and fusion glycoproteins were formulated with the cationic lipi...

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Bibliographische Detailangaben
Hauptverfasser: Pan, Chien-Hsiung, Jimenez, Gretchen S., Nair, Nitya, Wei, Qun, Adams, Robert J., Polack, Fernando P., Rolland, Alain, Vilalta, Adrián, Griffin, Diane E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Vaccine Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519314/
https://ncbi.nlm.nih.gov/pubmed/18524884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00120-08
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