Interleukin-23 Is Required for Development of Arthritis in Mice Vaccinated and Challenged with Borrelia Species

We recently hypothesized that T helper 17 (Th17) cells and their associated cytokines are involved in the development of arthritis following infection with Borrelia burgdorferi. Here, we show that interleukin-23 (IL-23), a survival factor for Th17 cells, is required for the induction of arthritis in...

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Bibliografiske detaljer
Main Authors: Kotloski, Nicholas J., Nardelli, Dean T., Peterson, Sara Heil, Torrealba, Jose R., Warner, Thomas F., Callister, Steven M., Schell, Ronald F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Microbial Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519303/
https://ncbi.nlm.nih.gov/pubmed/18579699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00129-08
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