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Tetanus Toxin and Antigenic Derivatives I. Purification of the Biologically Active Monomer

A procedure for the isolation of pure tetanus toxin in a lethal monomeric form was developed based on the extraction of whole cells and chromatographic techniques. A crude extract of toxin was obtained by hypertonic extraction of cells from a 72-hr culture of Clostridium tetani Massachusetts strain....

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Bibliographic Details
Main Authors: Murphy, Samuel G., Miller, Kent D.
Format: Artigo
Language:Inglês
Published: 1967
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC251926/
https://ncbi.nlm.nih.gov/pubmed/4962302
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