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Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells

There is increasing evidence that TGF-β family member cytokine bone morphogenetic protein (BMP)-4 plays different pathophysiological roles in the pulmonary and systemic circulation. Upregulation of BMP-4 has been linked to atherosclerosis and hypertension in the systemic circulation, whereas disrupt...

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Main Authors: Csiszar, Anna, Labinskyy, Nazar, Jo, Hanjoong, Ballabh, Praveen, Ungvari, Zoltan
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519199/
https://ncbi.nlm.nih.gov/pubmed/18539760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00180.2008
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